PROJECTS

iBeChange

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The iBeCHANGE project promotes personalized cancer prevention and lifestyle interventions to reduce cancer risk and improve patient outcomes.

Addressing Psychosocial and Lifestyle Risk Factors to Promote Primary Cancer Prevention: An Integrated Platform to Promote Behavioural Change

Recognizing that up to 40% of cancers are preventable through lifestyle changes, iBeCHANGE integrates behavioral science, digital health, and precision medicine to develop targeted prevention strategies. AI-driven insights and real-world data help empower individuals with tools for healthier living.

It will go beyond the state of the art of sustainable BC and EM by combining practice- and evidence-based knowledge coming from clinical psychology and BC theories with the potentialities of adaptive digital technologies and artificial intelligence.

Additionally, the project supports cancer survivors in post-treatment health management, reducing the risk of recurrence. iBeCHANGE collaborates with healthcare providers and policymakers to develop scalable, evidence-based prevention models that can be implemented across different healthcare systems.

Objectives:

  1. Develop personalized prevention strategies for cancer risk reduction.
  2. Use AI and digital tools to support healthier lifestyle choices.
  3. Provide evidence-based recommendations for policymakers.

 

Funded by: Horizon Europe – Mission on Cancer (HORIZON-MISS-2023-CANCER-01)

PROJECTS

Brecise

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The BRECISE project advances precision oncology by integrating molecular profiling and AI-driven diagnostics to personalize cancer treatment.

Biomarker Research and Evaluation for Clinical Implementation and Supporting Systems Enhancement

By developing next-generation liquid biopsy technologies and AI-powered diagnostic tools, BRECISE enables earlier detection of treatment resistance and ensures more effective therapy adjustments. These advancements help refine patient stratification, improving survival rates and treatment efficiency.

The project also focuses on integrating AI-driven diagnostics into routine clinical practice, fostering collaboration between research institutions, healthcare providers, and regulatory bodies. By establishing new standards for personalized cancer care, BRECISE contributes to making precision medicine more accessible across Europe.

Objectives:

  1. Develop advanced biomarkers for personalized cancer treatment.
  2. Implement AI-driven diagnostics for more accurate patient profiling.
  3. Support healthcare integration of precision oncology solutions.

 

Funded by: Horizon Europe – Innovative Health Initiative (HORIZON-JU-IHI-2024-07)

PROJECTS

Synthia

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The SYNTHIA project develops synthetic data solutions to enable AI-powered healthcare applications while ensuring privacy protection.

Synthetic Data Generation Framework For Integrated Validation Of Use Cases And AI Healthcare Applications

applications while ensuring privacy protection.

As digital transformation reshapes medicine, SYNTHIA creates high-quality, bias-free synthetic datasets for AI-driven healthcare solutions. These datasets mimic real-world medical data while safeguarding patient privacy, allowing for advanced research in genomics, imaging, and multimodal data analysis.

The project also establishes standardized metrics to evaluate synthetic data, ensuring its reliability for clinical applications. Through the SYNTHIA federated platform, researchers and clinicians can access validated datasets, fostering innovation in AI-driven healthcare while complying with strict data protection regulations.

Objectives:

  1. Develop advanced techniques for generating high-quality synthetic data.
  2. Create standardized benchmarks for evaluating synthetic data in healthcare.
  3. Establish an open federated platform for secure data sharing.

 

Funded by: Horizon Europe – Innovative Health Initiative (HORIZON-JU-IHI-2023-05)

PROJECTS

Althea

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The Althea project aims to enhance cancer prevention, diagnosis, and treatment through an integrated and patient-centered approach.

Tackling Mental Health Cancer Patients and Their Families: Digital Solutions for Better Care

By leveraging digital health tools, artificial intelligence, and genomic data, Althea aims to develop innovative strategies for early detection and tailored treatment. This will improve patient outcomes and reduce disparities in access to quality cancer care across Europe. The project also focuses on knowledge-sharing among healthcare professionals and supports policymakers with evidence-based recommendations to strengthen healthcare systems.

The Althea consortium promotes collaboration among leading European healthcare institutions, ensuring that advancements in oncology research translate into practical solutions for patients. By addressing key challenges in cancer prevention and care, the project aligns with broader EU efforts to reduce cancer incidence and mortality.

Objectives:

  1. Develop strategies for early cancer detection and personalized treatment.
  2. Facilitate collaboration among healthcare institutions for improved cancer care.
  3. Support policymakers with evidence-based recommendations.

Funded by: EU4Health Programme (EU4H-2023-PJ)

PROJECTS

ON-COME

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The ON-COME project aims to transform psychosocial and nutritional care for pediatric cancer patients, ensuring holistic and equitable support across Europe.

Paediatric Oncology Network and Communication on the Mind-Body-Environment Relationship

Focusing on children, adolescents, and young adults undergoing treatment for central nervous system tumors and leukemia, ON-COME addresses the significant emotional, neuropsychological, and nutritional challenges they face. The project will develop a Unified Service System to standardize best practices and provide digital tools that enhance personalized care.

ON-COME’s approach includes mapping existing care services, developing AI-powered patient-caregiver apps, and training healthcare professionals in holistic patient management. The project also pilots new support services in clinical settings, ensuring adaptability and effectiveness across different healthcare environments.

Objectives:

  1. Standardize psychosocial and nutritional care for pediatric oncology.
  2. Develop AI-driven digital tools to support patient care and decision-making.
  3. Provide specialized training for healthcare professionals to improve holistic care.

 

Funded by: EU4Health Programme (EU4H-2024-PJ-02)​

PROJECTS

Can.Heal

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The CAN.HEAL project focuses on aligning clinical and public health interventions to improve cancer diagnosis, treatment, and prevention through genomics and personalized medicine.

Building the EU Cancer and Public Health Genomics Platform

By leveraging next-generation sequencing (NGS) technologies and genomic profiling, CAN.HEAL aims to enhance early cancer detection, optimize treatment pathways, and improve risk assessment for patients and their families. The project also seeks to harmonize data interpretation across European cancer centers, ensuring equitable access to molecular diagnostics and precision therapies.

Beyond clinical applications, CAN.HEAL integrates genomics into public health strategies, incorporating polygenic risk scores, genetic counseling, and biobanking initiatives like the Genome of Europe. The project also explores ethical, legal, and societal aspects of genomic medicine to facilitate broader adoption within healthcare systems.

Objectives:

  1. Expand the use of NGS and molecular tumor profiling for personalized cancer care.
  2. Integrate genomic data into public health interventions for cancer prevention.
  3. Establish frameworks for cross-border data sharing and regulatory harmonization.

 

Funded by: EU4Health Programme (EU4H-2021-PJ2)

PROJECTS

Cancer Care Beacon

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The BEACON project aims to improve cancer diagnostics and treatment access across Europe, ensuring patients receive timely and effective care.

Cancer Care Beacon – Reducing Disparities Across the European Union

By integrating digital health technologies and AI-driven analysis, BEACON enhances early detection and risk assessment, allowing healthcare systems to provide more efficient, targeted cancer treatments. The project also emphasizes patient-centered care, developing personalized treatment pathways tailored to genetic and clinical profiles.

Additionally, BEACON fosters cross-border collaboration among healthcare professionals, researchers, and policymakers. By implementing shared learning initiatives, the project strengthens Europe’s oncology ecosystem and contributes to the advancement of precision medicine.

Objectives:

  1. Enhance early cancer detection using AI-driven diagnostics.
  2. Improve personalized treatment pathways for better patient outcomes.
  3. Strengthen European collaboration in oncology research and care.

 

Funded by: EU4Health Programme (EU4H-2021-PJ2)​